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<\/p>\nModified Voice Risk Score (MVRS) is a risk assessment tool that is used to determine an individual\u2019s risk of acquiring HIV. The MVRS tool uses 5 standardized questions and assigns a score to each response. The scores are specific to the questions and range from 0 to 2 based on a participant\u2019s response. The scores of each questions are added to give an overall score out of a maximum total score of 8. The scale is then used to determine an individuals risk with 0 meaning low or no risk whilst a score of 8 is high risk. The study requires us to identify individuals with a MVRS \u22655 and our study recruitment team have managed to identify 30% of our enrolled participants who have a MVRS of 8. This in turns means that the HPTN 084 team in Kuilsriver, Cape Town are targeting the correct population to answer the research question.<\/p>\n
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HPTN 084 (The LIFE Study) is a study being done to evaluate the safety and efficacy of the injectable agent, cabotegravir (CAB LA) compared to daily oral tenofovir disoproxil fumarate\/emtricitabine (TDF\/FTC), for pre-exposure prophylaxis (PrEP) in HIV-uninfected women. HPTN 084 has currently enrolled more than 3,200 women who are between the ages of 18 to 45 years old in sub-Saharan Africa who are at risk for acquiring HIV. HPTN 084 is important as PrEP agents are needed that do not depend on daily or near-daily pill-taking. The development of alternative agents for PrEP, and\/or more adherence-friendly schedules for currently available agents, could increase prevention choices and increase acceptability. Long-acting injectable agents have the potential to prevent HIV acquisition without relying on adherence to a daily oral regimen. Below is an image of the HPTN 084 study design.<\/p>\n
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Modified Voice Risk Score (MVRS) is a risk assessment tool that is used to determine an individual\u2019s risk of acquiring HIV. The MVRS tool uses 5 standardized questions and assigns a score to each response. The scores are specific to the questions and range from 0 to 2 based on a participant\u2019s response. The scores […]<\/p>\n","protected":false},"author":10471,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3256],"tags":[],"class_list":["post-1267","post","type-post","status-publish","format-standard","hentry","category-news"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/posts\/1267","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/users\/10471"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/comments?post=1267"}],"version-history":[{"count":6,"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/posts\/1267\/revisions"}],"predecessor-version":[{"id":1278,"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/posts\/1267\/revisions\/1278"}],"wp:attachment":[{"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/media?parent=1267"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/categories?post=1267"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.sun.ac.za\/dttc\/wp-json\/wp\/v2\/tags?post=1267"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}