Stellenbosch University
Pathology Research Day 2021
21 – 22 October 2021
Pathology research through the COVID-19 pandemic.

About Stellenbosch University Pathology Research day

The world is still in the grip of the COVID-19 pandemic. As far as possible, our staff and students have grown accustomed to the new and unique world we live in with social distancing, mask wearing, distance learning, “lockdown”, virtual meetings and conferences.
The Department of Pathology (Faculty of Medicine and Health Sciences) of Stellenbosch University will be hosting its Pathology Research Day on a virtual platform this year, on the afternoons of Thursday 21 October and Friday 22 October 2021.
The Department of Pathology at the National Health Laboratory Services Tygerberg and Stellenbosch University offers a comprehensive diagnostic pathology service to patients at Tygerberg Hospital and at the hospitals and clinics in its drainage area, while the Division of Forensic Medicine focuses on the provision of forensic pathology services. Almost the entire academic platform including training, teaching and research is based upon the service platform.
All presentations submitted by staff, postdoctoral fellows and students will be presented as powerpoint presentations with live Q&A sessions via the Microsfot Teams Application. The following divisions will be represented:
- Anatomical Pathology
- Chemical Pathology
- Haematological Pathology
- Medical Microbiology
- Medical Virology
- Forensic Medicine

Basic Medical Sciences
The basic medical sciences are a set of sciences looking at the molecular, cellular, and systems organization of the human body. It also involves an understanding of the biological mechanisms involved in adapting to environmental changes and disease.
This entails research to improve knowledge, interventions and technology that are of use in the healthcare sector.

Clinical Pathology Sciences
The branch of pathology dealing with the study of disease and disease processes by means of physical, chemical, microscopic, and serologic examinations. It also deals with the medico-legal forensic and anatomical autopsies.
This entails research to advance knowledge, interventions and technology, to improve patient care and outcomes in the clinical setting.

Event Date and Time
The event will stretch over two half days, from 13:30 – 17:00 on 21 October and 22 October 2021.
Please see the schedule below for more information regarding the presenters, time of presentations and question and answer sessions.
Featured Talks & Speakers
Please note that every Keynote address and the two Webinars (Basic Medical Sciences and Clinical Sciences) of the day will be different Webinars and thus require you to register for them independently.
Dr Tongai Maponga is a researcher and lecturer in the Division of Medical Virology at Stellenbosch University. His most recent work includes investigating SARS CoV-2 (COVID-19) in the South African population.
He will be discussing his experiences with SARS CoV-2 and the impact it has had on the South African medical fraternity.

Dr Tongai Maponga
COVID19: The experiences from the Tygerberg Virology Lab
21 October 2021 – 13:30
Dr Lulu Nair is a Senior lecturer in the Centre of Medical Ethics and Law at Stellenbosch University.
She is a clinician with experience in public health, clinical trial research in HIV and TB, GCP training and bioethics. Since graduating from the ARESA program she has served on the UKZN REC and the REC of the South African MRC.
She will be discussing the POPI Act and the implications on the medical field.

Dr Lulu Nair
POPIA: Implications for
Clinical Research
22 October 2021 – 13:30
Webinar Schedule 21 October 2021:
21 October 2021 | Basic Medical Sciences | Clinical Sciences | |
13:30 – 14:15 |
Keynote Address: COVID19: The experiences from the Tygerberg Virology Lab Dr T. Mapongo |
13:30 – 14:15 |
Keynote Address: COVID19: The experiences from the Tygerberg Virology Lab Dr T. Mapongo |
14:15 – 14:27 |
Development of a functional metagenomics approach for human gut resistome analysis. Amanda-Jo Venter |
14:15 – 14:27 |
The association between a plant-based diet and cardiovascular disease risk. Tatum Lopes |
14:27 – 14:39 |
The isolation and propagation of SARS-CoV-2: A skill in the fighting of a pandemic. Andrew Sutherland |
14:27 – 14:39 |
The incidence and factors associated with bone marrow involvement in lymphoma staging bone marrow examination from 2015-2019: a cross-sectional retrospective descriptive study. Kingsley Lohlun |
14:39 – 14:51 |
Molecular characterization and transmission dynamics of carbapenem-resistant Enterobacterales at Tygerberg Hospital. Moloto Kedisaletse |
14:39 – 14:51 |
Performance of urine methaqualone (mandrax) rapid test strips and effects of suspected drug interferences. Kelebogile Moremi |
14:51 – 15:10 | Q&A session | 14:51 – 15:10 | Q&A session |
15:10 – 15:30 | Tea and Coffee break | 15:10 – 15:30 | Tea and Coffee break |
15:30 – 15:35 |
Transfer of the SARS-CoV-2 Allplex™ assay from the laboratory-based CFX96 real-time RT-QPCR instrument to the portable paradna point-of-care device using heat-inactivated saliva samples. Moremi Kelebogile |
15:30 – 15:35 |
Inflammatory cytokine levels and lymphocyte subset distribution in multi-system inflammatory syndrome in children cases at Tygerberg Hospital. Edwin Mohlake |
15:35 – 15:40 |
Characterisation of cytomegalovirus envelope glycoprotein b genotypes in clinical samples at Tygerberg Hospital, Division of Medical Virology. Nothukela Mpanzi |
15:35 – 15:40 |
The occurrence of drug resistance-associated mutations among viraemic Hepatitis B samples obtained from the OX-SA Hep B cohort study participants. Bongani Mkhize |
15:40 – 15:45 |
The role of fluoroquinolone-induced bacterial stress responses in the development of antimicrobial resistance. Chante Brand |
15:40 – 15:45 |
Investigating meningitis in cases of sudden and unexpected death in infancy (SUDI) at the Tygerberg Medico-legal mortuary in the Eastern metropole of Cape Town. Simone-Odette Nortje
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15:45 – 15:50 |
Full-length genome sequencing of the Hepatitis E virus among South African patients. Bronwyn Roberts
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15:50 – 16:05 | Q&A session | 15:45-16:05 | Q&A session |
16:05-16:17 |
Variable functional phenotypes of inherited IL-12 receptor variants in patients with mendelian susceptibility to mycobacterial disease. Ansia Van Coller |
16:05-16:17 |
Thrombophagocytosis by neutrophils as a spurious cause of thrombocytopenia. Thinus Dicks |
16:17-16:29 |
Imatinib resistance: evaluating the role of pharmacogenetic variability in a South African chronic myeloid leukemia cohort. Chantal de Long |
16:17-16:29 |
Re-decontamination of liquid mycobacterial cultures: additional Mycobacterium tuberculosis culture yield in the era of Xpert MTb/Rif ultra®. Dawood da Costa |
16:30 – 16:35 |
The characterization of virulence in Coagulase-negative Staphylococci causing neonatal sepsis at Tygerberg Hospital. Stephanie Cloete |
16:29-16:41 |
Reference intervals for biochemical analytes in transgender individuals on hormone therapy. Morne Bezuidenhout |
16:35-16:40 |
Two-step algorithm: an acceptable alternative for detecting Clostridiodes difficile in resource limited-settings. Sarishna Singh |
16:41 – 16:46 |
Evaluation of a real-time PCR assay for the detection of bacterial meningitis pathogens at Tygerberg Hospital in the Western Cape. Malefu Moleleki |
16:40 – 16:50 | Q&A session | 16:46-16:56 | Q&A session |
Below are the 21 October 2021 Webinar Links
Webinar Schedule 22 October 2021:
22 October 2021 | Basic Medical Sciences | Clinical Sciences | |
13:30-14:30 |
Keynote Address: POPIA: Implications for Clinical Research Dr L. Nair |
13:30-14:30 |
Keynote Address: POPIA: Implications for Clinical Research Dr L. Nair |
14:30-14:42 |
Evaluation of an innovative new method for the quantitation of plasma cells on CD138 immunohistochemistry. Ethan Gantana |
14:30-14:42 |
All you need to know about: Hameer Vanmali |
14:42-14:54 |
Calprotectin (S100 A8/A9) as a marker of inflammation and treatment monitoring in cases of juvenile idiopathic arthritis in the Western Cape, South Africa. Christine Evert |
14:42-14:54 |
Variation in diagnostic requests and outcomes for hereditary thrombophilia over testing and under testing. Shareefa Isaacs |
14:55-15:10 | Q&A Session | 14:55-15:10 | Q&A Session |
15:10-15:30 | Tea and Coffee break | 15:10-15:35 | Tea and Coffee break |
15:30-15:35 |
E. coli subtyping of gastrointestinal samples from cases of sudden and unexpected death in infancy at the Tygerberg Medico-legal mortuary. Danielle Cupido |
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15:35-15:40 |
The carriage of plasmid-mediated antibiotic resistance genes in children from Cape Town communities. Danielle Wilck |
15:35-15:40 |
Grey platelet syndrome in a COVID-19 patient: A case study. Keshanya Moodley |
15:40-15:45 |
Application of personalised medicine using an integrated service and research (PM-ISR) approach extending from somatic to germline TP53 variant detection. Kelebogile Moremi |
15:40-15:45 |
The plot thickens – case report of a hyper viscous sample. Razia Banderker |
15:45-15:50 |
The gut mycobiota of young South African children: insights revealed by next-generation sequencing. Kristien Nel van Zyl |
15:45-15:50 |
Antibiotic resistant Staphylococci in South Africa – A one health approach. Remous Ocloo |
15:50-16:05 | Q&A session | 15:50-16:00 | Q&A session |
16:05-16:17 |
Comparative assessment of multiple serological assays to detect SARS-CoV-2 antibodies. Liret Swanepoel |
16:00-16:12 |
Haematological findings in adult patients with SARS-CoV-2 infection at Tygerberg hospital, Cape Town, South Africa. Helena Cornelissen |
16:17-16:29 |
Investigating the synergystic effect of silver nanoparticles with third generation cephalosporins against Acinetobacter baumannii. Luzell Britz |
16:12-16:24 |
The initial impact of the COVID-19 pandemic on new cancer diagnoses at the National Health Laboratory Service, Tygerberg Hospital. Abraham van Wyk |
16:30– 16:35 |
Milheiriço PCR based SCCmec typing scheme for the characterisation of Methicillin-Resistant Coagulase-negative Staphylococci. Farron Brooks |
16:25 – 16:30 |
A rare case of bone marrow based diagnosis of a mature large B-cell neoplasm with flow cytometry pitfalls. Kingsley Lohlun |
16:35-16:40 |
The role of accessory gene regulator systems on biofilm formation and stress response in Staphylococcus aureus. Kgomotso Maleka |
16:30-16:35 |
Investigating associations between sociodemographic factors and Human Rhinovirus infection in SUDI cases at Tygerberg Medico-legal Mortuary, within the East Metropole region of Cape Town. Hameer Vanmali |
16:40-16:50 | Q&A session | 16:35-16:50 | Q&A session |
Below are the 22 October 2021 Webinar Links
Join us online!
Due to the current COVID-19 pandemic, this year’s Pathology Research day will be virtual. Please feel free to join us.