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Stellenbosch University

Pathology Research Day 2021

21 – 22 October 2021

Pathology research through the COVID-19 pandemic.

About Stellenbosch University Pathology Research day

The world is still in the grip of the COVID-19 pandemic. As far as possible, our staff and students have grown accustomed to the new and unique world we live in with social distancing, mask wearing, distance learning, “lockdown”, virtual meetings and conferences. 
The Department of Pathology (Faculty of Medicine and Health Sciences) of Stellenbosch University will be hosting its Pathology Research Day on a virtual platform this year, on the afternoons of Thursday 21 October and Friday 22 October 2021.
The Department of Pathology at the National Health Laboratory Services Tygerberg and Stellenbosch University offers a comprehensive diagnostic pathology service to patients at Tygerberg Hospital and at the hospitals and clinics in its drainage area, while the Division of Forensic Medicine focuses on the provision of forensic pathology services. Almost the entire academic platform including training, teaching and research is based upon the service platform.
All presentations submitted by staff, postdoctoral fellows and students will be presented as powerpoint presentations with live Q&A sessions via the Microsfot Teams Application. The following divisions will be represented:

 

  1. Anatomical Pathology
  2. Chemical Pathology
  3. Haematological Pathology
  4. Medical Microbiology
  5. Medical Virology
  6. Forensic Medicine

 Basic Medical Sciences

The basic medical sciences are a set of sciences looking at the molecular, cellular, and systems organization of the human body. It also involves an understanding of the biological mechanisms involved in adapting to environmental changes and disease.

This entails research to improve knowledge, interventions and technology that are of use in the healthcare sector.

 Clinical Pathology Sciences

The branch of pathology dealing with the study of disease and disease processes by means of physical, chemical, microscopic, and serologic examinations. It also deals with the medico-legal forensic and anatomical autopsies.

This entails research to advance knowledge, interventions and technology, to improve patient care and outcomes in the clinical setting.

 

 

 

Event Date and Time

The event will stretch over two half days, from 13:30 – 17:00 on 21 October and 22 October 2021.

Please see the schedule below for more information regarding the presenters, time of presentations and question and answer sessions.

 

Featured Talks & Speakers

Please note that every Keynote address and the two Webinars (Basic Medical Sciences and Clinical Sciences) of the day will be different Webinars and thus require you to register for them independently.

Dr Tongai Maponga is a researcher and lecturer in the Division of Medical Virology at Stellenbosch University. His most recent work includes investigating SARS CoV-2 (COVID-19) in the South African population.

He will be discussing his experiences with SARS CoV-2 and the impact it has had on the South African medical fraternity.

 

Dr Tongai Maponga

COVID19: The experiences from the Tygerberg Virology Lab

21 October 2021 – 13:30

Dr Lulu Nair is a Senior lecturer in the Centre of Medical Ethics and Law at Stellenbosch University.

She is a clinician with experience in public health, clinical trial research in HIV and TB, GCP training and bioethics. Since graduating from the ARESA program she has served on the UKZN REC and the REC of the South African MRC. 

She will be discussing the POPI Act and the implications on the medical field.

 

Dr Lulu Nair

POPIA: Implications for
Clinical Research

22 October 2021 – 13:30

Webinar Schedule 21 October 2021:

 

21 October 2021 Basic Medical Sciences   Clinical Sciences
13:30 – 14:15

Keynote Address:

COVID19: The experiences from the Tygerberg Virology Lab

Dr T. Mapongo 

13:30 – 14:15

Keynote Address:

COVID19: The experiences from the Tygerberg Virology Lab

Dr T. Mapongo

14:15 – 14:27

Development of a functional metagenomics approach for human gut resistome analysis.

Amanda-Jo Venter 

14:15 – 14:27

The association between a plant-based diet and cardiovascular disease risk.

Tatum Lopes

14:27 – 14:39

The isolation and propagation of SARS-CoV-2: A skill in the fighting of a pandemic.

Andrew Sutherland

14:27 – 14:39

The incidence and factors associated with bone marrow involvement in lymphoma staging bone marrow examination from 2015-2019: a cross-sectional retrospective descriptive study.

Kingsley Lohlun 

14:39 – 14:51

Molecular characterization and transmission dynamics of carbapenem-resistant Enterobacterales at Tygerberg Hospital.

Moloto Kedisaletse   

14:39 – 14:51

Performance of urine methaqualone (mandrax) rapid test strips and effects of suspected drug interferences.

Kelebogile Moremi

14:51 – 15:10 Q&A session 14:51 – 15:10 Q&A session
15:10 – 15:30 Tea and Coffee break 15:10 – 15:30 Tea and Coffee break
15:30 – 15:35

Transfer of the SARS-CoV-2 Allplex™ assay from the laboratory-based CFX96 real-time RT-QPCR instrument to the portable paradna point-of-care device using heat-inactivated saliva samples.

Moremi Kelebogile

15:30 – 15:35

Inflammatory cytokine levels and lymphocyte subset distribution in multi-system inflammatory syndrome in children cases at Tygerberg Hospital.

Edwin Mohlake 

15:35 – 15:40

Characterisation of cytomegalovirus envelope glycoprotein b genotypes in clinical samples at Tygerberg Hospital, Division of Medical Virology.

Nothukela Mpanzi

15:35 – 15:40

The occurrence of drug resistance-associated mutations among viraemic Hepatitis B samples obtained from the OX-SA Hep B cohort study participants.

Bongani Mkhize 

15:40 – 15:45

The role of fluoroquinolone-induced bacterial stress responses in the development of antimicrobial resistance.

Chante Brand

15:40 – 15:45

Investigating meningitis in cases of sudden and unexpected death in infancy (SUDI) at the Tygerberg Medico-legal mortuary in the Eastern metropole of Cape Town.

Simone-Odette Nortje

 

15:45 – 15:50

Full-length genome sequencing of the Hepatitis E virus among South African patients.

Bronwyn Roberts

15:50 – 16:05 Q&A session 15:45-16:05 Q&A session
16:05-16:17

Variable functional phenotypes of inherited IL-12 receptor variants in patients with mendelian susceptibility to mycobacterial disease.

Ansia Van Coller

16:05-16:17

Thrombophagocytosis by neutrophils as a spurious cause of thrombocytopenia.

Thinus Dicks

16:17-16:29

Imatinib resistance: evaluating the role of pharmacogenetic variability in a South African chronic myeloid leukemia cohort.

Chantal de Long

16:17-16:29

Re-decontamination of liquid mycobacterial cultures: additional Mycobacterium tuberculosis culture yield in the era of Xpert MTb/Rif ultra®.

Dawood da Costa

16:30 – 16:35

The characterization of virulence in Coagulase-negative Staphylococci causing neonatal sepsis at Tygerberg Hospital.

Stephanie Cloete

16:29-16:41

Reference intervals for biochemical analytes in transgender individuals on hormone therapy.

Morne Bezuidenhout

16:35-16:40

Two-step algorithm: an acceptable alternative for detecting Clostridiodes difficile in resource limited-settings.

Sarishna Singh

16:41 – 16:46

Evaluation of a real-time PCR assay for the detection of bacterial meningitis pathogens at Tygerberg Hospital in the Western Cape.

Malefu Moleleki

16:40 – 16:50 Q&A session 16:46-16:56    Q&A session

 

Below are the 21 October 2021 Webinar Links

Webinar Schedule 22 October 2021:

 

22 October 2021  Basic Medical Sciences Clinical Sciences
13:30-14:30

Keynote Address:

POPIA: Implications for Clinical Research

Dr L. Nair

13:30-14:30

Keynote Address:

POPIA: Implications for Clinical Research

Dr L. Nair

14:30-14:42

Evaluation of an innovative new method for the quantitation of plasma cells on CD138 immunohistochemistry.

Ethan Gantana

14:30-14:42

All you need to know about:
Sudden unexpected death in infancy research in South Africa.

Hameer Vanmali

14:42-14:54

Calprotectin (S100 A8/A9) as a marker of inflammation and treatment monitoring in cases of juvenile idiopathic arthritis in the Western Cape, South Africa.

Christine Evert

14:42-14:54

Variation in diagnostic requests and outcomes for hereditary thrombophilia over testing and under testing.

Shareefa Isaacs

14:55-15:10                  Q&A Session 14:55-15:10            Q&A Session
15:10-15:30 Tea and Coffee break 15:10-15:35 Tea and Coffee break
15:30-15:35

E. coli subtyping of gastrointestinal samples from cases of sudden and unexpected death in infancy at the Tygerberg Medico-legal mortuary.

Danielle Cupido

 

15:35-15:40

The carriage of plasmid-mediated antibiotic resistance genes in children from Cape Town communities.

Danielle Wilck

15:35-15:40

Grey platelet syndrome in a COVID-19 patient: A case study.

Keshanya Moodley

15:40-15:45

Application of personalised medicine using an integrated service and research (PM-ISR) approach extending from somatic to germline TP53 variant detection.

Kelebogile Moremi

15:40-15:45

The plot thickens – case report of a hyper viscous sample.

Razia Banderker

15:45-15:50

The gut mycobiota of young South African children: insights revealed by next-generation sequencing.

Kristien Nel van Zyl 

15:45-15:50

Antibiotic resistant Staphylococci in South Africa – A one health approach.

Remous Ocloo

15:50-16:05 Q&A session 15:50-16:00 Q&A session
16:05-16:17

Comparative assessment of multiple serological assays to detect SARS-CoV-2 antibodies.

Liret Swanepoel

16:00-16:12

Haematological findings in adult patients with SARS-CoV-2 infection at Tygerberg hospital, Cape Town, South Africa.

Helena Cornelissen

16:17-16:29

Investigating the synergystic effect of silver nanoparticles with third generation cephalosporins against Acinetobacter baumannii.

Luzell Britz

16:12-16:24

The initial impact of the COVID-19 pandemic on new cancer diagnoses at the National Health Laboratory Service, Tygerberg Hospital.

Abraham van Wyk

16:30– 16:35

Milheiriço PCR based SCCmec typing scheme for the characterisation of Methicillin-Resistant Coagulase-negative Staphylococci.

Farron Brooks

16:25 – 16:30

A rare case of bone marrow based diagnosis of a mature large B-cell neoplasm with flow cytometry pitfalls.

Kingsley Lohlun

16:35-16:40

The role of accessory gene regulator systems on biofilm formation and stress response in Staphylococcus aureus.

Kgomotso Maleka 

16:30-16:35

Investigating associations between sociodemographic factors and Human Rhinovirus infection in SUDI cases at Tygerberg Medico-legal Mortuary, within the East Metropole region of Cape Town. 

Hameer Vanmali

16:40-16:50              Q&A session 16:35-16:50           Q&A session

 

Below are the 22 October 2021 Webinar Links

Join us online!

Due to the current COVID-19 pandemic, this year’s Pathology Research day will be virtual. Please feel free to join us.

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